Spurs have picked up just 15 points from 10 league games and they are 8th in the table.
The Portuguese manager was relieved of his duties after just four months into the job and the defeat against Manchester United is believed to have been the straw that broke the camel’s back.
A statement from Tottenham read: “The club can today announce that Nuno Espirito Santo and his coaching staff Ian Cathro, Rui Barbosa and Antonio Dias have been relieved of their duties.”
Paratici said: “I know how much Nuno and his coaching staff wanted to succeed and I regret that we have had to take this decision. Nuno is a true gentleman and will always be welcome here. We should like to thank him and his coaching staff and wish them well for the future.”
The Italian manager has been out of a job since leaving his post at Inter Milan and he could prove to be a sensational appointment for the Londoners.
Conte helped Inter Milan win the Italian league title last season and he has managed in the Premier League before with Chelsea.
The Italian is a proven winner across multiple leagues and he managed to win the Premier League title with the Blues during his time at Stamford Bridge.
Tottenham will be expected to compete for a place in the top four this season after their significant summer outlay and it remains to be seen whether the Premier League side can secure a deal for Conte and turn their season around.
The report further states that the two parties are in advanced negotiations right now and the Italian is in London ahead of a possible announcement.
Conte was linked with a move to Tottenham before Nuno Espirito Santo was appointed as the club’s manager but the deal collapsed eventually.
Apparently, the club’s sporting director Fabio Paratici has a strong relationship with the 52-year-old Italian manager having worked with him at Juventus and he is believed to be the key driving force behind the appointment of Antonio Conte.