Venue: San Siro
Inter Milan have failed to beat Shakhtar Donetsk in their last three matches across all competitions. All three matches have ended in a draw.
Inter Milan are unbeaten in their last six matches across all competitions and they have managed to win four of those outings.
Shakhtar Donetsk have managed to win four of their last five matches across all competitions.
Head to head
Inter Milan and Shakhtar have faced each other six times since 2005 and the Italian outfit have managed to pick up two wins and four draws.
Latest performances in all competitions
Inter Milan: DWWWDW
Shakhtar Donetsk: WWLWW
The Italian champions managed to pick up a morale-boosting 3-2 win over Napoli at the weekend and they will be full of confidence heading into this contest.
The Italian giants are unbeaten in their last six matches against Shakhtar and they will be hoping to extend that run with a positive result at home this week.
Possible Inter Milan starting line-up
Samir Handanovic (GK); Milan Skriniar, Andrea Ranocchia, Federico Dimarco; Ivan Perisic, Nicolo Barella, Marcelo Brozovic, Hakan Calhanoglu, Matteo Darmian; Lautaro Martinez, Joaquin Correa
The Ukrainian outfit are in impressive form coming into this game and they will be hoping to grind out a positive result here.
They have managed to keep a clean sheet in their last three matches against inter and it will be interesting to see if they can step up and produce a quality performance here.
The visitors have conceded nine goals in four Champions League group games so far and they will have to tighten up defensively if they want to get something out of this contest.
Possible Shakhtar Donetsk starting line-up
Anatolii Trubin (GK); Ismaily, Valeriy Bonda, Nykola Matviienko, Dodo; Maycon, Marcos Antonio; Tete, Mykhailo Mudryk, Manor Solomon; Fernando
Inter Milan 2-1 Shakhtar Donetsk